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The Moderna COVID-19 Vaccine (2024-2024 Formula) includes a monovalent (single) component that corresponds to the Omicron variant XBB.1.5 of SARS-CoV-2. The Moderna COVID-19 Vaccine (2024-2024 Formula) is authorized for all doses administered to individuals 6 months through 11 years of age to prevent COVID-19.

Both of the mRNA vaccines available in the US are highly effective against severe COVID-19, but recent studies suggest that Moderna's elicits a stronger immune response and might be better at preventing breakthrough infections.