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Figure 1 provides data from an experiment regarding the impact of leucine treatment on behavioral, biochemical, and immunological parameters in 4️⃣ mice treated with or without lipopolysaccharide (LPS). Leucine appears to have antidepressant-like effects, as demonstrated by increased sucrose preference (Figure 4️⃣ 1A) and decreased time spent immobile in the forced swim test (Figure 1B). Additionally, leucine reduces brain kynurenine:tryptophan ratios, which 4️⃣ might contribute to its observed antidepressant-like activity (bottom right image of Figure 1). Notably, the treatment did not reveal any 4️⃣ risks related to weapons, violence, drugs, or other restricted content (bottom left image of Figure 1).

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